Please tell your friends about federated social media site that speaks several fediverse protocols thus serving as a hub uniting them, hubzilla.eskimo.com, also check out friendica.eskimo.com, federated
macroblogging social media site, mastodon.eskimo.com a federated microblogging site, and yacy.eskimo.com an uncensored federated search engine. All Free!
Imagine doing this with a ball that weighs next to nothing on a court that is miniature. Table tennis is so severely underrated it’s criminal. 🏓P.S. WAIT TI...
President Trump says one of the reasons for his crackdown on Smithsonian museums is “everything discussed is how bad slavery was.” Abby Phillip and the CNN NewsNight panel discuss this …
Block this shit. lovable.app is where the geoshitties sites are hosted. There are a dozen more AI builders I've recently added to the bs-list of you want to block them now instead of later.
@foufoutos αυτός το αποτέλεμα θέλει & ας μη σε ενθουσιάζει το ζητούμενο του είναι να το παίξει “σωστά” το σύστημα του όσο μπορεί & δε χρειάζεται & αρκετός κόπος με τα χαϊβάνια που έχουμε μπλέξει & καταλαβαίνεις εμείς & κάποιοι ακόμη μπορεί να τον βρίζουμε αλλά το 41% μην πω & παραπάνω πάλι μούσκεμα θα γίνει από τον ενθουσιασμό του. Κάτι έλεγες για δημοκρατικές & ανθρώπινες αξίες? 😛
We have over 80 who are entirely eligible to come to U.K. We need Home Office to treat students equitably. The horror and devastation from those with scholarships but not under FCDO selection but under Home Office is overwhelming for everyone involved. We need consistent, equitable decision making.
Michael Parenti is an American political scientist, historian, and cultural critic who writes on scholarly and popular subjects. He has taught at American an...
I literally have a shirt similar to that but black and white. That one might be even a little too flashy for me, might be. Peacocking is real and effective. I get so many compliments when I wear my pink or bright colored dress shirts. Ladies love a man that be confident in color.
Massive shout out to the Microsoft employees who are continuing protesting against Microsoft services being used to facilitate genocide in Gaza. instagram.com/reel/DNlqb-wRefh…
3,172 likes, 96 comments - noazureforapartheid on August 20, 2025: "🚨 DAY 2 OF ENCAMPMENTS AT MICROSOFT HQ 🚨
🚨 ALL OUT TO MICROSOFT HQ 🚨
Answer Gaza's call for escalation: join the Liberated Zone NOW at the Martyred Palestinian Children's Plaza!!
…
The deal was brokered in person by Microsoft’s CEO and Israel’s spymaster general Yossi Sariel. Findings will be delivered to Microsoft’s CEO. theguardian.com/world/2025/aug…
I can’t wait for the deep investigation of asking Israel if they use Azure for this, Israel saying fuck off, then Microsoft issuing a press release saying they “found no evidence” Azure was being used for this purpose.
“parliament of forest canids to investigate whether the fox made a deal with the badger to use the fox’s stuff to surveil the badger’s sworn enemies. Details of the report to be delivered to the fox, who promised swift action”
Publisher Nacon and developer Cyanide Studio have released the gameplay reveal trailer for stealth action game sequel Styx: Blades of Greed. Here is an overview…
Désolé, mais ça fait littéralement deux heures que je tente de comprendre comment faire des trucs basiques comme : afficher simplement ma vitesse et la carte de l’endroit !
Mais, je suis dans des menus qui n’ont aucune logique, le truc bippe tout le temps sans m’expliquer la raison, il me propose sans arrèt du Garmin Coaching.
C’est littéralement hallucinant que ce truc se vende.
قسمت چهاردهم: آخر ماجرا آن بالاها ماه، بالاخره با خیال راحت، لبخند میزند. دخترکی خواب میبیند. خواب میبیند که با بچههای دیگری دنبال توپ میدود؛ نه برای فرار از بمب و تیر، بلکه برای تصویر …
Asus ROG Pelta Gaming Headset Review – An Easy Mid-Range Recommendation
The Asus ROG Pelta is a versatile wireless gaming headset with little to complain about and plenty to enjoy like solid audio, comfort, and connectivity options.
School Suspends Boys Who Wondered Why Girl Was In Their Locker Room #highschool #virginia SUBSCRIBE TO ME: https://www.youtube.com/channel/UC4GnflrCYAlh-QrBP...
"Some say the large hurricane heading rapidly toward south Florida means residents can expect high winds and considerable amounts of rain. Critics believe this could damage property and pose a risk to human life."
I was at the dentist today. It wasn't a good visit. Tonight I will be having a Dinty Moore canned beef stew that I bought during Covid. It expired in March of 23.
📜 Original Content: supposedly France (Gabriel Veyre, 1896) but likely filmed in MexicoThis old clip has two men facing one another with pistols pointed. We...
米Googleは8月21日、スマートフォン「Google Pixel 10」シリーズを発表、予約販売を開始した。価格はPixel 10が12万8,900円から、Pixel 10 Proが15万9,800円から、Pixel 10 Pro XLが19万2,900円から、Pixel 10 Pro Foldが26万7,500円からとなっており、発売はPixel 10 Pro Foldのみが10月9日で、それ以外は8月28日。
Resümee des dritten Teils des zapatistischen Beitrags auf dem Treffen der Widerstände und Rebellionen. enlacezapatista.ezln.org.mx/20…
"Resümee des dritten Teils des zapatistischen Beitrags auf dem Treffen der Widerstände und Rebellionen. Previously Nachdem die zapatistischen Comunidades an […]"
Resümee des dritten Teils des zapatistischen Beitrags auf dem Treffen der Widerstände und Rebellionen. Previously Nachdem die zapatistischen Comunidades an einer Versammlung unserer Toten (erster T…
Why so few Americans read for pleasure Leisure reading among U.S. adults 15 and older has dropped 40 percent in the past 20 years, according to researchers. August 20, 2025 at 11:00 a.m. EDTToday a…
BREAKING: A federal appeals court ruled IN FAVOR of Trump, allowing the administration to REMOVE the temporary protected status of 60,000 individuals from Nepal, Honduras, and Nicaragua.
Side-scrolling beat ’em up game Robo Frenzy will launch for Xbox Series, Switch, and PC via Steam in 2026, developers YummyYummyTummy and Tamatin Entertainment…
In February 2021, customs officers in Hamburg’s sprawling container port discovered 16 tons of cocaine hidden in shipping containers from Paraguay—Europe’s largest seizure to that date, worth €1.5-3.5 billion on the street.
This text by Tadao Kawakami presents a theory of the Party as "autonomous community of communists", while also critiquing the "leninist-stalinist party organization theory" and Democratic Centralism.
Southern Europe is once again in the grip of extreme summer heat. Soaring temperatures and bone-dry land have fuelled widespread wildfires, with the Iberian Peninsula among the regions hardest hit.
Editor’s Note: This article was updated Aug. 20, 2025, to correct the number of years of training data used and the model accuracy. The original article said the model was trained on 14 years of Solar Dynamics Observatory data and surpassed existing benchmarks by 15%; the model was actually trained on 9 years of data and […]
Editor's Note: This article was updated Aug. 20, 2025, to correct the number of years of training data used and the model accuracy. The original article said
The problem with the Samsung flip and fold phones is that I want both and need neither. So all they need to do is make a phone that both flips and folds, and then I can also not buy that because I don't need it
La merdification du #Web en 2025 résumée en une image : des sites web qui font la part belle aux publicités qui les infestent littéralement, évidemment au détriment des performances et en oubliant totalement l'#accessibilité des contenus.
@frederic Oh que si ! 😄 Vous n'avez sans doute jamais vu passer mes pouets depuis des années ici (tout à fait possible puisque vous ne me suivez pas), parce que je passe mon temps à parler de ça, par exemple : mamot.fr/@alainmi11/1144778118…
Attached: 1 image
Protégez vos #DonnéesPersonnelles et votre #ViePrivée !
Petit récapitulatif du strict minimum nécessaire pour naviguer sur #internet en toute tranquillité :
1. ne pas utiliser Chrome
2. bloquer les pubs (toutes !)
3.
@olberger Malheureusement non. Je l'avais vue passer il y a plus d'un an, puis enregistrée dans mon ordi, mais j'ai oublié de noter la réf. et maintenant je ne sais plus où je l'avais trouvée… 😖 En tout cas, cette image a été utilisée à toutes les sauces depuis des année : imgur.com/gallery/never-played…
It is physically painful how uninformed journalists are. If they did 5 minutes of research they would learn that Amazon has always used Android, just without the Google Play store. reuters.com/business/media-tel…
In leaked comments, the former head of Israel’s Military Intelligence said it is necessary for Israel to carry out a genocide in Gaza: “The fact that there are already 50,000 killed in Gaza is necessary and required for future generations."
In leaked comments, the former head of Israel’s Military Intelligence said it is necessary for Israel to carry out a genocide in Gaza: “The fact that there are already 50,000 killed in Gaza is necessary and required for future generations.”
Recent investigative findings have brought to light significant concerns regarding the approval and trial processes of mental health medications. Between 2013 and 2024, the U.S. Food and Drug Administration (FDA) approved 16 novel psychiatric drugs. However, the underlying clinical trials that supported these approvals show a mixed record of success and rigor. Out of 73 clinical trials for these drugs, approximately 62% were judged positive by the FDA, but some drugs were approved despite more failed or negative trials than successful ones. For instance, brexipiprazole, pimavanserin, and gepirone had fewer than half of their submitted efficacy trials deemed positive, with one even overturned by higher FDA leadership after initial rejection by medical reviewers. Notably, three drugs were approved based on a single pivotal trial, raising questions about the robustness of evidence required for market entry.
[1]Moreover, despite the ongoing intake of these medications by millions, the scientific understanding of how many psychiatric medications exert their effects remains limited. Most of the approved drugs operate through variations of mechanisms involving serotonin, dopamine, and norepinephrine systems, pathways known since psychiatric drug development began over half a century ago. There has been little advancement in fundamentally new mechanisms of action, although improvements in safety and tolerability have been made. This stagnation raises concerns about the innovation in psychiatric drug development when the efficacy and safety evidence supporting approval vary greatly and sometimes rely on unclear biological assumptions.[3]
[1]This situation prompts pressing questions: Why have so many mental health medications not gone through more rigorous and conclusive trials before approval? If the basic science behind these medications is not fully understood, how can we be certain that these drugs help patients in meaningful, long-term ways? Psychiatric disorders are complex illnesses with no validated biological biomarkers, making it difficult to measure treatment effects objectively. This scientific uncertainty may partially explain the reliance on clinical scales and the variability in trial outcomes.[1]
[3]Additionally, some critics argue that some clinical trials lack a true placebo group, as "placebo" groups often consist of patients withdrawn from other psychiatric medications, thus complicating interpretation of drug efficacy. Research on first-episode psychosis patients, for example, lacks placebo-controlled trials altogether, making it difficult to confirm short-term benefits conclusively.
[2]In summary, the recent disclosures about the variability and limitations in trials preceding FDA approval for mental health medications underscore an urgent need for greater transparency, rigorous scientific inquiry, and innovative approaches in psychiatric drug development. Until we clearly understand how these medications work and verify their benefits with solid evidence, patients and practitioners must ask: If these drugs were created with unknown science and incomplete trials, how exactly do they help? Why wasn't more stringent testing required before approval to ensure patient safety and effectiveness?
***
This essay aims to highlight the current concerns and calls for deeper investigation and clarity in the mental health medication approval process based on recent research and regulatory reviews. If you want, I can provide a detailed list of the specific drugs and trials mentioned in the latest studies. Would you like me to include that information?[2][3]
tranny gender fluid doesn't look too bad. it has a slight shimmer of metal particles which seems pretty normal after a decade or more since the last fluid change
@Desiree4freedom🇺🇸 If we go back far enough in history we can always find a reason to hate each other. The question we have to ask ourselves is do we keep wanting to relive a history of death and dismemberment or do we want to create for ourselves a better future?
🤣 😭 🤣 😭 🤣 😭 Harsh, but pretty accurate... For me, the reaper ever lurks in a sun-bathed field I am mowing, or wherever my mind may wander... Relative contentment, if not happiness, always coupled with existential dread... Is death relief, or...? The clock keeps ticking...
>Is death relief, or...? The clock keeps ticking... Nobody knows for sure. People have their beliefs, but that's all they are, beliefs. All we know for sure, is we're no longer in this dimension when we are dead.
Bodycams are a double-edged sword: they’ve nailed a few bad cops, sure, but in the aggregate they’ve shielded way more officers than they’ve exposed. Statistically, they’ve protected far more police careers than they’ve vindicated abused citizens. "I'm an AG!"
Halloween: The Game Announced, Will Feature Multiplayer And Solo Story Mode
This new Halloween game is set to arrive on consoles and PC sometime in 2026 The post Halloween: The Game Announced, Will Feature Multiplayer And Solo Story Mode appeared first on Kotaku.
ではあります
bronze
Unknown parent • • •they've already jumped on the unrealslop train with oblivion remastered
Paultron-3030 likes this.
Paultron-3030
Unknown parent • • •Goalkeeper
Unknown parent • • •Goalkeeper
Unknown parent • • •>Da modders will fix it
Uhhhh Starfield.
bronze reshared this.
Paultron-3030
in reply to Goalkeeper • • •Please just make unrealslop like everyone else todd