friendica (DFRN) - Link to source

Piracetam - Fucking Dopes Administration


Here is the safety profile for Piracetam:

Toxicity and harm potential

Adverse effects, although rare and of short duration are limited to anxiety, insomnia, drowsiness, headaches and agitation. It may be safe for up to 18 months in humans at doses of 3.2g daily with one year-long study in ambulatory patients with Alzheimer's using 8g daily reporting no side effects.[10] However, a possibility for adverse drug-drug interactions persists for piracetam due to it interacting with blood in an anti-clotting manner (and such, caution should be taken when pairing piracetam with pharmaceutical blood thinning agents such as Warfarin or potent nutraceutical options).

No fatal overdoses associated with piracetam use have been reported as of 2016. In animal models (rodents, dogs, and marmoset), an LD50 failed to be established at the dosage of 8-10g/kg.

Regardless, it is strongly recommended that one use harm reduction practices when using this substance.
Lethal dosage

The median lethal dosage (LD50) of piracetam has not been officially published as it has low abuse potential, but the typical dosage is two grams once to three times a day.
Dependence and abuse potential

The chronic use of piracetam can be considered as not addictive with a low potential for abuse. It does not seem to be capable of causing psychological dependence among certain users.

Tolerance to many of the effects of piracetam develops with prolonged and repeated use. This results in users having to administer increasingly large doses to achieve the same effects. After that, it takes about 3 - 7 days for the tolerance to be reduced to half and 1 - 2 weeks to be back at baseline (in the absence of further consumption). Piracetam may presents cross-tolerance with all racetam nootropics, meaning that after the consumption of piracetam certain nootropicss such as aniracetam and pramiracetam may have a reduced effect.
Dangerous interactions

Piracetam showed nonselective MAO activity in a rat study.[11][12] Piracetam and MAOIs are a potentially dangerous combination. It is likely that MAOIs could increase the effects of piracetam unpredictably. Taking this chemical while on prescription MAOIs is strongly discouraged.

As you can see, with the exception of MAOI's it is exceptionally safe.

I have been using it to treat tinnitus and restore lost high frequency
hearing (in my case hearing went from upper limit of 8Khz back to 17Khz) with
100% success for more than ten years.

Now, because the FDA is blocking imports, I can't get it.

I would like to encourage everyone to write the FDA and their congress critters to put a stop to this. With such a good safety profile there is absolutely NO justification for this and a lot of people, myself included, will needlessly suffer.

friendica (DFRN) - Link to source

Digital Ocean Spam / Virus


Posted on October 16, 2020

We have received a large number of spams containing a virus from Digital Ocean address spaces. We are receiving these exclusively from digital address space. For every one of these I have sent e-mail to their published abuse address, abuse@digitalocean.com and to their NOC at noc@digitalocean.com.

I have yet to receive a single reply and as a consequence I initially started blocking individual addresses these came from. But still they continue. Now I am blocking entire address blocks as we receive this virus / spam. I am also sending this to blacklist maintainers as well as using it as a source to train our baysian filters.

At present the following address space is blocked for incoming mail:

167.172.127.122 REJECT Spam Digital Ocean
165.227.147.88 REJECT Spam Digital Ocean
128.199.13.160 REJECT Digital Ocean Virus
159.203.181.43 REJECT Digital Ocean Virus
188.166.64.227 REJECT Digital Ocean Virus
209.97.155.51 REJECT Digital Ocean Virus
204.48.23.113 REJECT Digital Ocean Virus
104.248.58.145 REJECT Digital Ocean Virus
198.199.120.66 REJECT Digital Ocean Virus
138.197.0.0/16 REJECT Digital Ocean Virus
143.110.128.0/17 REJECT Digital Ocean Virus
142.93.0.0/16 REJECT Digital Ocean Virus
159.203.0.0/16 REJECT Digital Ocean Virus
159.89.0.0/16 REJECT Digital Ocean Virus
159.65.0.0/16 REJECT Digital Ocean Virus
174.138.0.0/17 REJECT Digital Ocean Virus
64.227.0.0/17 REJECT Digital Ocean Virus
188.166.0.0/17 REJECT Digital Ocean Virus

I don’t like to do this but when a company will not respond to complaints and the spams are viral in nature, I am left with little choice. I have also submitted a copy to clam-av folks to generate a signature for

friendica (DFRN) - Link to source

Unannounced Kernel Upgrade


Posted on October 16, 2020

I apologize for the unannounced kernel upgrade this morning but it was done rapidly because a security flaw was discovered in 5.8 and earlier kernels that I wanted to eliminate as rapidly as possible. We are now running 5.9 kernels.

This took two rounds last night because my first build of 5.9 was not correctly configured for our servers so I had to rebuild, re-install, and reboot again.

5.9 has a minor bug in the NFS code that is printing some warnings. It involves a race condition when a client attempts to open a file it doesn’t have permissions to open. Since the open would have failed anyway on the basis of permissions I do not believe this bug has any significant operational consequences other than making noise in the kernel logs.

I checked bugzilla and there is already a bug report filed though given the relatively low severity I doubt it will get rapid attention, but I’m added to the notification list so we will update again once fixed.

friendica (DFRN) - Link to source

5.9 Tickless Kernels Available now:

eskimo.com/.../linux-5.9-tickl…
eskimo.com/.../linux-5.9-tickl…

Both of these kernels are tickless idle. Which means when a clock tick happens, the it is serviced and processes scheduled only if there is work pending. This saves a lot of unnecessary CPU wake-ups and is especially valuable on laptops where it will save battery or on virtual machines where you have many virtual machines on one physical host. In such a situation just servicing clock interrupts can eat more CPU than running client services.

These Linux kernels are provided with no warantee. Use them only if you agree to accept all risk for any damage to your machine or it's contents.

The are several differences between these kernels and those provided by Ubuntu, Debian, Mint, etc.

First, these are all upstream kernels, they have no vendor patches and only occasional minor patches from me.

Second, they are tickless kernels. CONFIG_NO_HZ is set, CONFIG_NO_HZ_FULL is not set. On the client kernel, CONFIG_HZ_1000=y, on the server kernel, CONFIG_HZ_100=y.

The server kernel is non-premptive, the client kernel is fully preemptive. This provides maximum processing ability on the server, minimal latency on client machines.

There are three '.deb' packages provided. Download all three and install with dpkg -i *.deb.

These will work on Ubuntu, Mint, Debian, Zorin, JeLinux, MxLinux, and other Debian based distributions.

in reply to Nanook

I use on four physical hosts, one workstation which is running the "client" version, it is an i7-9700k machine with 1G WD Blue SSD and Intel graphics, and three physical hosts, two i7-6700k with 64G RAM and one i7-6850k machine with 128G of RAM, all have KVM-QEMU virtual hosts and two of the three are also NFSv4 servers to each other, a variety of virtual hosts, NFSv3 servers to some older machines running Redhat 6.2 that are UltraSparc based, and one NFSv2 SunOS 4.1.4 machine. The virtual hosts are web servers, shell servers, mail servers, and various application servers. So it's a fairly well rounded load. Going from a tickfull to tickless kernel approximately halved the loads on the physical hosts, going from version 5.7 to 5.8 reduced the webserver response time on a WordPress site from about 800ms to 285ms for full page load, that was a HUGE improvement, but going from 5.8 to 5.9 shaved only about 10ms off of load times, a modest improvement. There was quite a lot of work in scheduler and NFS both on 5.8 so it was more of a major win for us, 5.9 did rework Intel graphics so some help for my workstation not a lot for servers. This friendica node, friendica.eskimo.com/ is running on a 56G virtual machine which is running under the i7-6700k machine. All of the machines here presently running this kernel are Ubuntu 20.04 but I have the 5.8 kernels running under Mint, Debian, MxLinux, Zorin, and a few others, and they will be upgraded by this weekend.
This entry was edited (4 years ago)

friendica (DFRN) - Link to source

Oil Burning Furnace Repair


I've got an antique 50's vintage oil burning furnace that needs to be replaced but I haven't got the money to replace it with what I want to just yet but it needs some work that is probably beyond the value of the furnace. I have a modern high efficiency burner in it but it has burned a hole in the firebox so the firebox needs to be repaired or replaced. In addition the bearings are squeaking on the squirrel cage fan so it's going to take a dive at some point but they've been noisy for years, the firebox is the safety and immediate concern.

Can anyone point me at someone who could repair an antique like this?
In the long run I want to replace the whole affair with a heat pump but that requires some remodeling to accommodate. I am in Shoreline, Washington just north of Seattle.

friendica (DFRN) - Link to source

Superman


I love this, such an interesting melding of multiple cultures and past and present technologies to make something with a wonderful message and I think this shines a light on what is possible for humanity, it's not just "Why can't we all get along", it's "Why can't we all get together and blend our talents and strength to create a synergy of mankind that is even greater than the sum of it's components?" and this video demonstrates that synergy in four short minutes. Awesome!

friendica (DFRN) - Link to source

Friendica Retention Period


Does anyone know if there is a way to increase the length of time a friendica node retains posts? I'd really like to be able to go back farther than four pages worth of posts which seems to be about the limit.

I'm not anywhere near maxed out on disk:
Filesystem Size Used Avail Use% Mounted on
204.122.16.128:/social 2.6T 61G 2.4T 3% /social


And I'm more than willing to purchase bigger drive(s) if/when that becomes
necessary.

in reply to Nanook

You don't speak about facts, only about ideas

A single neuron doesn't exist: neurons exist to be connected, a single neuron can be connected to 10000 other neurons and that's what making it special
You have neurons everywhere except in your hairs and nails, feelings are technically interconnected neurons sharing information about their environment, internal (skin, organs, even bones) or external (what we hear, see, smell, taste or touch)

So, we could define a person at biological level as "a neuron net and dependancies"
The fetus isn't connected to the mother neural net, it's a parasitic entity to the point of view of body (explaining why so many embryo never reach the fetus step: the body kill them)

In fact, nature practices abortion on a daily routine, it's estimated that between 50% and 90% fecundated eggs never end in a fetus. That's unwilling abortion, you should worry more about that

And about your picture: it's not a 12-16 weeks fetus. The only cases when abortion is practiced after the legal term is when the mother's life is threatened (and if the mother dies, the fetus dies) or if the fetus is already dead. So you're using a personal drama to your propaganda. Jesus is disappointed

Furthermore, MAGA boys claim the right to kill born following their own vision of right. So there's this question you didn't answered: if killing an unborn is a major crime, is killing a born a bigger crime?